Disease-Modifying Antirheumatic Drugs (conventional DMARDs)
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Overview
Conventional DMARDs are a group of medications that slow or stop the progression of autoimmune and inflammatory diseases, particularly rheumatoid arthritis and lupus. Unlike biologics, these are small-molecule drugs taken orally.
How do disease-modifying antirheumatic drugs (conventional dmards) work?
Conventional DMARDs work through various mechanisms to suppress the overactive immune system. They reduce inflammation and prevent joint destruction by interfering with immune cell proliferation, cytokine production, or antigen presentation. Their effects develop gradually over weeks to months.
Drugs in this class
- Hydroxychloroquine (Plaquenil)