Antimuscarinics (Overactive Bladder)
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Overview
Medications that block muscarinic (acetylcholine) receptors in the detrusor muscle of the bladder, reducing involuntary bladder contractions. Antimuscarinics are first-line pharmacological therapy for overactive bladder symptoms including urinary urgency, frequency, and urge incontinence.
How do antimuscarinics (overactive bladder) work?
Competitively block muscarinic M2 and M3 receptors in the detrusor muscle of the bladder, reducing involuntary bladder contractions and increasing bladder capacity.
Drugs in this class
- Tolterodine (Detrol, Detrol LA)