Erbitux®

What is Erbitux used for   

      Erbitux is a chemotherapy medicine (medicine used to kill cancer cells) that is given in a vein (I.V. infusion). It is used to treat a type of cancer of the colon or rectum that has spread to other areas of the body (EGRF-expressing metastatic colorectal carcinoma).  Erbitux is used:

      with another chemotherapy medicine called irinotecan in people whose EGFR-expressing metastatic colorectal cancer is not or no longer shrinking with irinotecan alone

      alone in people with EGFR-expressing metastatic colorectal cancer who cannot take irinotecan

Special Warnings with Erbitux:       

      Erbitux may cause severe reactions during I.V. infusion that may result in death.  The reactions include symptoms that happen suddenly such as trouble breathing, an itchy swelling on the skin (hives), and low blood pressure.  These severe reactions can happen with any Erbitux infusion, but have happened more often the first time Erbitux is given.   People that have severe infusion reactions with Erbitux must have their infusion stopped right away, and cannot be treated with Erbitux again.

      Erbitux may cause a serious lung condition called interstitial lung disease that results in inflammation, scarring, and hardening of the lungs.

      Erbitux often causes skin reactions such as an acne-like rash, drying, cracking, inflammation, and infections.  These reactions may be worsened by sun exposure.

General Precautions with Erbitux:

      Wear sunscreen, hats, and protective clothing, and limit sun exposure during treatment with Erbitux.

      Women who can become pregnant should avoid pregnancy and use contraception during treatment with Erbitux.

What should I tell my health care provider?

What are some possible side effects of Erbitux? (This list is NOT a complete list of side effects reported with Erbitux.  Your health care provider can discuss with you a more complete list of side effects.)

      infusion reaction

      skin reactions

      lung disease

      fever

      infection in the blood

      kidney failure

      blood clot in the lung

      loss of water and salt from the body (dehydration)

      diarrhea

      acne-like rash

      tiredness

      diarrhea

      nausea

      abdominal pain

      vomiting

      fever

      constipation

Reports of patients? experience after Erbitux became available:

For more detailed information about Erbitux, ask your health care provider or pharmacist.

Canadian Pharmacy Information
This information is provided for Canadian citizens.  The FDA, due to the current state of their regulations, has taken the position that virtually all shipments of prescription drugs imported from a Canadian pharmacy by a U.S. consumer will violate the law.